Hookworm: Difference between revisions

(Created page with "==Background== ==Clinical Features== *Morbidity is related to number of worms harbored in intestines *Light infections often asymptomatic *Heavier infections with variety of...")
 
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==Background==
==Background==
*Necator americanus
*Larvae penetrate through intact skin on contact with feces-contaminated soil
**Enter the bloodstream, ascend the trachea, descend the esophagus to differentiate into adult worms, and migrate to the upper intestine where they attach to the mucosal wall and feed on host blood
*Commonly occurs in warmer climates (tropics, Southeast United States). <ref>Becker BM, Cahill JD: Parasitic Infections, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 131:p 1751-1762</ref>


==Clinical Features==
==Clinical Features==
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*Heavier infections with variety of manifestations including GI symptoms (abdominal pain, diarrhea, blood in stool, rectal prolapse), malaise, weakness, impaired cognitive / physical development, malnutrition<ref>Wilcox S, Thomas S, Brown D, Nadel E.  “Gastrointestinal Parasite.”  The Journal of Emergency Medicine, 2007; 33(3):277-280</ref></ref>
*Heavier infections with variety of manifestations including GI symptoms (abdominal pain, diarrhea, blood in stool, rectal prolapse), malaise, weakness, impaired cognitive / physical development, malnutrition<ref>Wilcox S, Thomas S, Brown D, Nadel E.  “Gastrointestinal Parasite.”  The Journal of Emergency Medicine, 2007; 33(3):277-280</ref></ref>
*Iron-deficiency [[anemia]]
*Iron-deficiency [[anemia]]
*Hypochromic microcytic anemia
**Adult worms attach to intestinal wall to feed, causing ongoing luminal blood loss
**Adult worms attach to intestinal wall to feed, causing ongoing luminal blood loss


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==Sources==
==Sources==
<references/>
<references/>
<ref>Becker BM, Cahill JD: Parasitic Infections, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 131:p 1751-1762</ref>


[[Category:ID]]
[[Category:ID]]
[[Category:TropMed]]
[[Category:TropMed]]

Revision as of 21:06, 24 January 2015

Background

  • Necator americanus
  • Larvae penetrate through intact skin on contact with feces-contaminated soil
    • Enter the bloodstream, ascend the trachea, descend the esophagus to differentiate into adult worms, and migrate to the upper intestine where they attach to the mucosal wall and feed on host blood
  • Commonly occurs in warmer climates (tropics, Southeast United States). [1]

Clinical Features

  • Morbidity is related to number of worms harbored in intestines
  • Light infections often asymptomatic
  • Heavier infections with variety of manifestations including GI symptoms (abdominal pain, diarrhea, blood in stool, rectal prolapse), malaise, weakness, impaired cognitive / physical development, malnutrition[2]</ref>
  • Iron-deficiency anemia
  • Hypochromic microcytic anemia
    • Adult worms attach to intestinal wall to feed, causing ongoing luminal blood loss

Differential Diagnosis

Workup

Management

  • Albendazole 400 mg x 1 dose (high efficacy) OR mebendazole 500 mg x 1 dose (low to moderate efficacy)
  • Iron supplements in anemia

Disposition

See Also

External Links

Sources

  1. Becker BM, Cahill JD: Parasitic Infections, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 131:p 1751-1762
  2. Wilcox S, Thomas S, Brown D, Nadel E. “Gastrointestinal Parasite.” The Journal of Emergency Medicine, 2007; 33(3):277-280

[1]

  1. Becker BM, Cahill JD: Parasitic Infections, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, (Ch) 131:p 1751-1762