Dextrose

Pediatric Hypoglycemia Dextrose Chart

Category Age Glucose Treatment Initial IV Bolus Maintenance Dose
Neonatal <2mo <40 D10W 2.5-5 mL/kg 6 mL/kg/h
Pediatric 2mo-8yrs <60 D25W 2 mL/kg

D10W:

  • 6 mL/kg/h for first 10 kg
  • + 3 mL/kg/h for 11–20 kg
  • + 1.5 mL/kg/h for each additional kg >20 kg
Adult >8yrs <70 D50W 50mL (1 amp) OR 1 mL/kg
  • Consider diluting the D25 or D50 bolus, with NS 1-to-1, as those concentrations may be sclerosing to veins
  • Recheck 5 minutes after dose and repeat dose if low.
  • Consider glucagon IM/SQ if IV access is not readily available

Dextrose Comparison

  • D50W
    • 25gm dextrose in 50mL sterile water (25g/50ml = 50% dextrose)
  • D10W
    • 25gm dextrose in 250mL sterile water (25gm/250mL = 10% dextrose)
  • D5W
    • 25gm dextrose in 500mL sterile water (25gm/500mL = 5% dextrose)

Rule of 50

Divide 50 by the type of dextrose solution to arrive at rate in ml/kg

  • Adult (D50): 50/50 = 1 ml/kg
  • Pediatric (D25): 50/25 = 2 ml/kg
  • Infant (D10): 50/10 = 5 ml/kg

See Also